Article - Issue 54

CELL AND GENE THERAPY (CGT)

Article - Issue 54

The JAPAC Drug Development Market

Article - Issue 54

What do We Know About Albumin Formulations?

Article - Issue 54

COCKTAIL NANOPARTICLES

Article - Issue 54

Next-Generation Approach through Advanced Research and Engineering Techniques in Cell Based Therapy

Article - Issue 54

Biomarkers for Cardiovascular diseases

Article - Issue 54

DRUG ANALYSIS IN SPORTS

Article - Issue 54

Innovative Trial Designs

Article - Issue 54

Ensuring Safety in Geriatric Medicine Use

Article - Issue 54

Nanoparticle Biomimetics as an Avenue to Personalised and Precision Medicine

Article - Issue 54

Enhancing Pharmacovigilance through the Scope of Artificial Intelligence

LATEST NEWSRead more...

10

May 2024

SN Bioscience Granted FDA Fast Track Status for Small Cell Lung Cancer Therapy

SN Bioscience Co Ltd under the leadership of CEO Park Younghwan made an announcement on May th regarding the FDAs decision to grant Fast Track Designation for SNB a novel polymer nanoparticle anticancer medication currently undergoing clinical trials for small cell lung cancer

10

May 2024

Arcellx and Kite Continue Progress with Advances in Anito-Cel Multiple Myeloma Program

Arcellx Inc and Kite a Gilead Company have jointly announced significant operational advancements in their collaborative effort on the anitocabtagene autoleucel program for multiple myeloma treatment

09

May 2024

CytomX Therapeutics Shares Positive Phase 1a Dose Escalation Findings for Monotherapy CX-904 (EGFRxCD3 PROBODY® T-Cell Engager)

CytomX Therapeutics Inc announced positive initial findings from the ongoing CX Phase a dose escalation clinical study The study focuses on CX a novel masked conditionally activated PROBODY

09

May 2024

ProQR Unveils Preclinical Proof of Concept Findings for AX-0810 Axiomer™ RNA Editing Initiative Targeting NTCP in Combatting Cholestatic Conditions

ProQR Therapeutics NV revealed significant preclinical findings at the American Society of Gene Cell Therapy Annual Meeting in Baltimore Maryland Their proprietary Axiomer RNA editing

08

May 2024

NSG BioLabs Drives Biotech Innovation in Singapore and Southeast Asia through EnterpriseSG and Merck Collaborations, Supported by Investments from Celadon Partners and ClavystBio

NSG BioLabs a prominent provider of biotech coworking laboratory and office spaces in Singapore

08

May 2024

BioVersys Expands Collaboration with GSK and Boosts Series C Funding by CHF 12.3 Million

BioVersys AG a clinicalstage biopharmaceutical company and GSK plc a global biopharma leader have announced an expansion of their strategic collaboration

press releasesRead more...

10

May 2024

Moleculin Announces U.S. Patent Issue Notification for Lipid-Based Delivery Technology for Annamycin

Moleculin Biotech Inc a clinical stage pharmaceutical company with a broad portfolio of drug candidates targeting hardtotreat tumors and viruses today announced it has received an Issue Notification

10

May 2024

Formosa Pharmaceuticals Licenses Clobetasol Propionate Ophthalmic Suspension to Tabuk Pharmaceuticals for Post-Ocular Surgery Treatment

Taiwanbased Formosa Pharmaceuticals announced today that the company has entered into an exclusive licensing agreement with Tabuk Pharmaceuticals Manufacturing Company

10

May 2024

FDA-approved TIVDAK®: Targeting Tissue Factor in Cervical Cancer

US FDA granted full approval for Seagen Incs TIVDAK tisotumab vedotin targeting tissue factor TF for the treatment of patients with recurrent or metastatic

10

May 2024

Annovis Announces Unblinding of the Buntanetap Phase III Data in Parkinson’s Disease

Annovis Bio Inc a clinicalstage drug platform company developing novel therapies for neurodegenerative diseases today announced successful completion of data cleaning

10

May 2024

Anaptys to Receive $50 Million in a Capped Non-Recourse Monetization from Amended Agreement with Sagard in Exchange for Additional Jemperli Royalties

AnaptysBio Inc a clinicalstage biotechnology company focused on delivering innovative immunology therapeutics today announced the execution of an amended agreement with Sagard Healthcare

09

May 2024

Neurocrine Biosciences Announces Initiation of Phase 1 Clinical Study Evaluating Effects of NBI-1117567 in Healthy Adults

Neurocrine Biosciences Inc today announced the initiation of its Phase firstinhuman clinical study to evaluate the safety tolerability pharmacokinetics and pharmacodynamics of investigational compound

EventsRead more...

13 - 15

May 2024

Global Meet on Pharmaceutics and Drug Delivery

Prague, Czech Republic

14 - 14

May 2024

Drug Discovery Biology & Bioinformatics

New Jersey, USA

15 - 16

May 2024

Global Pharma

Barcelona, Spain

15 - 16

May 2024

8th Decentralized & Hybrid Clinical Trials

Pennsylvania, USA

15 - 16

May 2024

3rd Diversity in Clinical Trials

Pennsylvania, USA

15 - 16

May 2024

Pharmacovigilance Europe Congress 2024

London, UK

15 - 17

May 2024

Bioprocessing Summit

Berlin, Germany

15 - 16

May 2024

CHEMUK 2024

NEC, Birmingham, UK

KNOWLEDGE BANK

Interviews
Porton Pharma Solutions and Codexis Launch Global Partnership
PARTNERSHIP
Codexis Inc and Porton Pharma Solutions Ltd announce a strategic collaboration to deploy Codexis worldleading biocatalyst technology within Portons global custom intermediate and active pharmaceutical ingredients API development and manufacturing business The partnership will accelerate the creation and commercialization of new lowcost sustainable manufacturing processes exploiting the benefits of...

Articles
Lipid Excipients and Formulation Development
The successful introduction of commercial lipidic formulations of cyclosporine as Sandimmune in followed by its reformulation as Neoral has raised interest of the lipidbased drug delivery technology over the past two decades With a greater understanding of the various functions lipids may have in boosting oral bioavailability

Research Insights
3D Mesh Processing using GAMer 2 to enable Reaction-Diffusion Simulations in Realistic Cellular Geometries
Recent advances in electron microscopy have enabled the imaging of single cells in D at nanometer length scale resolutions An uncharted frontier for in silico biology is the ability to simulate cellular processes using these observed geometries

Case Studies
Effect Of Cold Spells And Theirmodifiers On Cardiovascular Disease Events: Evidence From A Double Prospective Study
AbstractCardiovascular disease CVD is the most common cause of death globally remaining a considerable burden both in terms of health and costs As in many countries CVD mortality in the UK exhibits a marked seasonal variation more people die during the winter months DecemberMarch than in other periods of the year and the majority of deaths occur

Techno Trends
UoFL Researchers Discovered Novel Technology that Shows Promise Fighting Coronavirus
The researchers at the University of Louisville have discovered a technology for their research in fighting the severe acute respiratory syndrome coronavirus SARSCoVresponsible for the COVID pandemic

White Papers
Driving value creation through medical affairs in China
After more than three decades of fast economic growth China has entered the new normal stage marked by a moderate and stable domestic GDP growth rate Healthcare has been elevated to a national level agenda by the current leadership with the releasing of China Health

Advisory Board

Brian D Smith

Nigel Cryer FRSC

Quang Bui

Gervasius Samosir

Tamara Miller

Imedla Leslie Rillon

Andri Kusandri

Nicoleta Grecu

Alessio Piccoli

Pramod Kashid

Neil J

EDITORIAL SECTION

STRATEGY
Accelerating Cell and Gene Therapy Treatments to Patients with the Right CDMO Outsourcing Model
Approximately million people worldwide are living with a rare disease and about half of those affected by rare diseases are children

RESEARCH DEVELOPMENT
An introduction to FDA’s Human Factors Engineering Requirements for Drug-Device Combination Products
Although less well known than other drug development phases human factors engineering HFE is critical to meeting regulatory expectations for drugdevic...

CLINICAL TRIALS

MANUFACTURING
Just in Time Manufacturing Creating more sustainable supply chains
Drug development has transformed immeasurably over the past decade Even before the Covid pandemic and the conflict in Ukraine

Information Technology
Challenges and Advantages of Using Artificial Intelligence in Pharma
Many advanced largescale AI initiatives still need to be proved successful in Pharma

EXPERT Talk
Innovative Biotech Ecosystem in Singapore and Asia
Singapore has had a multidecade longterm vision for building a worldclass biomedical cluster

CELL AND GENE THERAPY (CGT)

The JAPAC Drug Development Market

What do We Know About Albumin Formulations?

COCKTAIL NANOPARTICLES

Next-Generation Approach through Advanced Research and Engineering Techniques in Cell Based Therapy

Biomarkers for Cardiovascular diseases

DRUG ANALYSIS IN SPORTS

Innovative Trial Designs

Ensuring Safety in Geriatric Medicine Use

Nanoparticle Biomimetics as an Avenue to Personalised and Precision Medicine

Enhancing Pharmacovigilance through the Scope of Artificial Intelligence

LATEST NEWSRead more...

10

SN Bioscience Granted FDA Fast Track Status for Small Cell Lung Cancer Therapy

10

Arcellx and Kite Continue Progress with Advances in Anito-Cel Multiple Myeloma Program

09

CytomX Therapeutics Shares Positive Phase 1a Dose Escalation Findings for Monotherapy CX-904 (EGFRxCD3 PROBODY® T-Cell Engager)

09

ProQR Unveils Preclinical Proof of Concept Findings for AX-0810 Axiomer™ RNA Editing Initiative Targeting NTCP in Combatting Cholestatic Conditions

08

NSG BioLabs Drives Biotech Innovation in Singapore and Southeast Asia through EnterpriseSG and Merck Collaborations, Supported by Investments from Celadon Partners and ClavystBio

08

BioVersys Expands Collaboration with GSK and Boosts Series C Funding by CHF 12.3 Million

press releasesRead more...

10

Moleculin Announces U.S. Patent Issue Notification for Lipid-Based Delivery Technology for Annamycin

10

Formosa Pharmaceuticals Licenses Clobetasol Propionate Ophthalmic Suspension to Tabuk Pharmaceuticals for Post-Ocular Surgery Treatment

10

FDA-approved TIVDAK®: Targeting Tissue Factor in Cervical Cancer

10

Annovis Announces Unblinding of the Buntanetap Phase III Data in Parkinson’s Disease

10

Anaptys to Receive $50 Million in a Capped Non-Recourse Monetization from Amended Agreement with Sagard in Exchange for Additional Jemperli Royalties

09

Neurocrine Biosciences Announces Initiation of Phase 1 Clinical Study Evaluating Effects of NBI-1117567 in Healthy Adults

EventsRead more...

13 - 15

Global Meet on Pharmaceutics and Drug Delivery

14 - 14

Drug Discovery Biology & Bioinformatics

15 - 16

Global Pharma

15 - 16

8th Decentralized & Hybrid Clinical Trials

15 - 16

3rd Diversity in Clinical Trials

15 - 16

Pharmacovigilance Europe Congress 2024

15 - 17

Bioprocessing Summit

15 - 16

CHEMUK 2024

TOP ARTICLES

1

Syringe-like Bacterial Nanomachine Emerges as Potential Therapeutics Delivery Device

Chanchal Kumawat

Protein Biochemist

2

Nanotechnology Strategies for Age –Related Macular Degeneration

Aira Sarkar

Department of Pharmaceutical Science and Technology, Institute of Chemical Technology (ICT)

Sathish Dyawanapelly

Department of Pharmaceutical Science and Technology, Institute of Chemical Technology (ICT)

3

There’s Finally Hope to Alleviate the Burden of Chronic Diseases

Raman Singh

Chief Executive Officer, Juniper Biologics

4

Mussel-inspired Bio-adhesives

Amisha Raikar

Pharmacy (B-Pharm), Goa University

5

Nano-Carrier based Smart Drug Delivery Systems

Sidharth Mehta

Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science & Technology

Nikita Yadav

Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science & Technology

KNOWLEDGE BANK