Pharma Articles
Articles on key issues related to the pharma industry from the heads of leading pharmaceutical companies and pharma industry experts across the globe. The pharma industry articles' section focuses on current and emerging issues in areas such as Strategic developments in the pharma industry, pharmaceutical R&D, drug discovery, clinical trials, pharmaceutical manufacturing, biopharmaceuticals, and information technology.
Beyond the Cold Chain
Lyophilisation and spray drying as superior biologic platforms
The global healthcare landscape is witnessing a seismic shift Biological drugs once considered a niche frontier have now become the vanguard of modern medicine successfully addressing some of the most complex health challenges of our time including refractory cancers rare genetic disorders and chron...Applying Human Factors Engineering to Generic Combination Products
Human factors engineering HFE is a key element in developing an effective medical device and focuses on ensuring that a devices design is wellmatched to its intended users In contrast to developing an entirely new combination product where the HFE process involves a variety of activitiesThe Role of Bioinformatics in Accelerating Translational Research
The advent of highthroughput technologies has resulted in a massive influx of biological data into public repositories For example platforms such as the Sequence Read Archive SRA have amassed over petabytes of sequencing data housing millions of datasets generated from global studies Kodama et al...From Gene Editing to Network Medicine
How CRISPR, Programmable Gene Circuits, and AI-Driven Intrinsic Network Pharmacology May Transform Next-Generation Drug Discovery
Biomedicine is undergoing a profound transformation driven by the convergence of genomics artificial intelligence and systems biology Traditional drug discovery largely focused on identifying a single molecular target and designing a compound capable of modulating that target While this strategy has...Integrated by Design
Strategic pathways for drug-led combination products
Combination products which integrate a drug andor biologic component with a medical device component are increasing globally Because they do not fit neatly into a single category regulation of these products can be difficult to navigateThe Therapeutics Landscape of Miniproteins
marks years since the approval of the first monoclonal antibody mAb muromononabCD OKT in Over four decades the pharmaceutical industry has accumulated an extraordinary body of knowledge on how to discover engineer manufacture and safely administer antibodybased therapeuticsDecoding Antisense Oligonucleotides: Mechanisms, Applications, and Future Directions
Antisense oligonucleotides ASOs constitute a class of synthetic nucleic acidbased therapeutics that target RNA molecules with high specificity These short chemically modified strands bind complementary RNA sequences thereby modulating gene expression at the posttranscriptional level ASOs offer preci...Nanomedicine
Its significance in the Pharmaceutical Sector
The Indian pharmaceutical sector is witnessing remarkable expansion influenced by several elements including patent expirations governmental support and the increasing prevalence of chronic illnesses It is projected that the industry will attain a valuation of US billion by the year and is acknowl...Rethinking How Medicines Work
Why timing may matter as much as dose
A visit to the doctors office often begins with routine questions Age weight blood pressure current medications and medical history are all taken note of These questions may appear simple but they are central to determining the dosage of a medicine someone might be prescribedThe Value in Decolonising Drug Discovery
Why Partnership Beats Extraction
The simplest way to discuss extraction in drug discovery or taking knowledge from a source without attribution is that its a bad habitTo frame it as a historical relic is to misunderstand its persistent and modern reality Cells being taken from a tumor of Henrietta Lacks without consent in remains...APAC’s Rising Role in Neurodegenerative Disease Research and Development
Neurodegenerative diseases represent one of the most pressing global health challenges of the coming decades driven by aging populations increasing disease prevalence and the absence of curative therapies While historically concentrated in North America and Europe research and development efforts in...Novel Developments in Drug Delivery Systems
From nanobots to smart therapeutics
Discovery of new active pharmaceutical compounds is no longer the only essential factor for therapeutic innovation clinical success increasingly depends on how effectively those agents are delivered to the intended site of actionChanging Paradigms in Use of AI in Chemical Sciences
During my postgraduate studies three decades ago I was drawn to the emerging fields of cheminformatics and computeraided molecular design CAMD Working with Silicon Graphics workstations and advanced computational tools of that era significantly shaped my scientific direction Throughout my career I h...The New Pharmacovigilance Era
Technology, precision, and patient-centric safety
When purchasing a new kitchen appliance or trying a new skincare product most of us instinctively take small safety steps checking reviews looking for quality certifications or doing a quick patch test These everyday habits reflect a simple principle we rarely trust something new without validating...3D Printing
Redefining Clinical Manufacturing in the Pharmaceutical Industry
The pharmaceutical industry is undergoing a profound transformation driven by advanced manufacturing technologies that challenge conventional models of drug development clinical supply and production Among these innovations threedimensional D printing and more specifically semisolid extrusion SSE pr...
