KNOWLEDGE BANK

Interviews

Life Sciences - Clinical, TNT Asia

Director
Clinical trials have very detailed and precise processes and the logistical elements of these processes are critical Recent revisions to the pharmaceutical industrys regulatory laws as well as improved patent laws in countries such as Japan China and India have led to the burgeoning clinical trials market in Asia

Articles

Harnessing Plant Potential

Biotechnology has achieved remarkable milestones with plantbased production of biotherapeutics emerging as a compelling innovation Traditionally biotherapeutics have been manufactured through microbial fermentation or animal cell cultivation but plants offer a greener more costeffective alternative Thanks to advances in genetic engineering and biological processing

Research Insights

New Developments For Antibody-drug Conjugate-based Therapeutic Approaches

Abstract The clinical success of Adcetris brentuximab vedotin and Kadcyla adotrastuzumab emtansine has sparked clinical development of novel ADCs These powerful anticancer agents are designed to allow specific targeting of highly potent cytotoxic agents to tumor cells while sparing healthy tissues Despite the use of tumorspecific antibodies

Case Studies

Analytics Stories: A Case Study from Quintiles

As I have shared within other posts within this series businesses are using analytics to improve their internal and external facing business processes and to strengthen their right to win within the markets that they operate For pharmaceutical businesses strengthening the right to win begins and ends with the drug product development lifecycle I remember for example t...

Techno Trends

Revolution Medicines Introduces Breakthrough Elironrasib for the Treatment of KRAS G12C-Mutated Non-Small Cell Lung Cancer

Revolution Medicines has introduced elironrasib as the first and only investigational therapy to receive FDA Breakthrough Therapy designation for the treatment of adult patients with KRAS GCmutated

White Papers

Cloud Computing in the Laboratory Informatics Solutions and Validation Approaches

In the modern business environment, a significant portion of work is conducted using computerized systems. Many solutions are used to complete tasks, including simple desktop programs like email and Microsoft Office to enterprise-wide, global systems like ERP (Enterprise Resource Planning), MES (Manufacturing Execution System), and LIMS

TOP ARTICLES

1

Emerging Technologies in Pharmaceutical Sciences

Abhishek Rungta

Abhishek Rungta is the Founder and CEO of INT. (Indus Net Technologies), a full-stack digital transformation company serving 500+ enterprise clients across 45 countries. He writes on enterprise AI adoption, digital transformation, and long-term business building.

2

Effect of Size of Protein Therapeutics on Brain Pharmacokinetics following Systemic Administration

Hsueh-Yuan Chang

Chang supports the preclinical-to-clinical PKPD translation and human efficacious dose prediction of new biological entities at Boehringer Ingelheim. Dr. Chang obtained his MS and Ph.D. in Pharmaceutical Sciences at the University at Buffalo. Under Dr. Dhaval Shah’s mentorship, Dr. Chang investigated antibody and protein therapeutic disposition in the rat brain using large-poremicrodialysis and developed a translational brain PBPK model for monoclonal antibodies.

 

Dhaval K Shah

Dhaval K Shah is an Associate Professor of Pharmaceutical Sciences at the State University of New York at Buffalo. Prior to becoming the faculty Prof. Shah served as a Principle Scientist in the ‘Translational Research-Modeling & Simulation’ group at Pfizer Inc. His research focuses on understanding the determinants for the absorption, distribution, metabolism, and elimination (ADME) of protein therapeutics. His lab uses the principles of Pharmacokinetics-Pharmacodynamics (PK-PD) Modeling & Simulation to support the discovery, clinical translation, and late phase development of novel biologics like engineered antibodies, multi-specific proteins, immuno-oncology agents, engineered T cells, and antibody-drug conjugates.

 

Shengjia Wu

Shengjia Wu is a PhD student in the pharmaceutical sciences at the State University of New York at Buffalo. His research focuses on understanding and modeling the macromolecule distribution in the central nervous system.

 

Yingyi Li

Yingyi Li gained her master’s degree of pharmaceutical sciences in University at Buffalo. When Yingyi was a master student, she was working in Dr. Dhaval Shah’s lab and became more experienced in PBPK modeling. Yingyi is currently a scientist in the field of pharmacometrics and translational PK-PD in Enhanced Pharmacodynamics.

 

3

The Rapidly Evolving Landscape of Cancer Therapeutics

Rajesh Kumar

Rajesh Kumar is an Assistant Professor of Pharmaceutical Sciences at Kerala University of Health Sciences, India. He has been teaching Diploma, Bachelor, and Doctor of Pharmacy students for several years and is actively involved in research. He has authored more than 19 papers and is a reviewer for Bentham Science Publishers. His research includes applying the principles of pharmaceutical sciences, omics technologies, computational biology, and bioinformatics in the broad areas of cancer research, ethnopharmacology, drug delivery, targeting, and formulations.

 

Seetha Harilal

Seetha Harilal is an Assistant Professor of Pharmacology at Kerala University of Health Sciences, India. She has several years of experience in teaching Diploma, Bachelor, and Doctor of Pharmacy students and is actively pursuing research. She has authored more than 22 papers and is a manuscript reviewer for Bentham Science Publishers, Frontiers in Public Health, Frontiers in Medicine, and Archives of Medical Research (Elsevier). Her research includes the diverse areas of pharmacology and therapeutics, phytopharmaceuticals, cancer research, neurological disorders, and the application of omics technologies, computational pharmacology, and bioinformatics.

 

4

QSAR - Changing the Landscape of Antidiabetic Drug Discovery

Smriti Sharma

Smriti Sharma Bhatia is an associate professor of chemistry at Miranda House, University of Delhi, India.  Her academic and research interests include Computational chemistry and drug design. Currently, her research group is focused on the design of oral drug formulations for Type 2 diabetes mellitus. She is a popular science communicator.

 

5

Why Pharma's Safety Net Must Follow the Medicine Home

Barbara Van Rymenam

Barbara works closely with leaders across pharmaceutical, medical devices and solution providers serving healthcare organisations - all of whom are using digital product identities.
Much of her time is spent with product owners and senior leaders in packaging, operations, anti-counterfeit, manufacturing, and with system integrators. She is focused on protecting patient safety at scale, serving leadership with trusted data and improving efficiency through innovative solutions.

Barbara's background spans innovation strategy, partnership development, marketing and commercial roles and cross-functional leadership in highly regulated settings. She is known for her collaborative and pragmatic approach, working alongside teams to explore long-term roadmaps that balance progress with responsibility.

Barbara cares deeply about how healthcare systems evolve without compromising what matters most. She is always open to conversations with leaders who are navigating similar challenges and looking to move forward responsibly.
 

press releasesRead more...

Insitro Designed Machine Learning Models for Small Molecule in vivo Pharmacokinetic Behavior Prediction Now Available in Lilly TuneLab

Insitro the AI company unlocking causal human biology to systematically generate highimpact therapeutics today announced that the advanced machine learning models that insitro built with Eli Lilly

Lotus Pharmaceutical Announces Completion of UroVaxom® Product Rights Acquisition in South Korea

Lotus Pharmaceutical Co Ltd Taiwan Stock Exchange a global pharmaceutical company headquartered in Taiwan today announced the completion of the acquisition of the South Korea product rights

XtalPi Debuts Kodexia™, the World's First Closed-Loop siRNA Platform Combining Generative AI with First-Principles Modeling

XtalPi Holdings Limited HKEX an AI and roboticsdriven drug and materials discovery company today debuted Kodexia the industrys first closedloop small interfering RNA siRNA

ITOCHU Announces Strengthening of Drug Development Support Through the Use of AI-Driven Drug Discovery Technologies

ITOCHU Corporation announced today that it has signed a capital alliance agreement with MOLCURE Inc headquartered in Kawasaki City Kanagawa Prefecture Satoshi Tamaki Representative Director

GC Cell and QuantHealth Collaborate to Optimize Clinical Development of GCC2005

GC Cell a leader in the cell and gene therapy CGT sector within the biopharmaceutical industry and QuantHealth the global leader in AIpowered clinical trial simulation have announced a collaboratio

EpiSign and Geneyx Announce Partnership to Integrate Genomic and Epigenomic Analysis for Rare Disease

EpiSign Inc and Geneyx Genomex Ltd today announced a partnership to advance the integration of genomic and epigenomic analysis for raredisease interpretation

EventsRead more...

12 - 13

Oct 2026

Pharmaceutics 2026

Village Hotel Changi, Singapor...

12 - 13

Oct 2026

2nd International Conference on Drug Discovery

Village Hotel Changi, Singapor...

14 - 15

Oct 2026

PDA Aseptic Manufacturing Excellence Conference

Pullman East Melbourne, Austra...

21 - 23

Oct 2026

21 - 22

Oct 2026

22 - 23

Oct 2026

PDA Aseptic Symposium 2026

Congress Square Nakanoshima, O...

26 - 28

Oct 2026

ACHEMA Middle East 2026

RICEC, Riyadh, KSA, Saudi Arab...

26 - 28

Oct 2026

World Orphan Drug Congress

RAI, Amsterdam, Netherlands

LATEST NEWSRead more...

Mint Pharmaceuticals and Bayer Expand Medicine Distribution in Canada

Mint Pharmaceuticals and Bayer have expanded their distribution partnership in Canada to include several additional medicines across womens health cardiovascular care and anticoagulation

Halozyme Expands argenx Collaboration to Include Two Additional Development Targets

Halozyme Therapeutics has expanded its global collaboration and licence agreement with argenx to develop and commercialise subcutaneous formulations for two additional exclusive targets using its ENHANZE drug delivery technology

CSL and Alentis Partner to Advance Lixudebart for Rare Kidney and Liver Diseases

CSL and Alentis Therapeutics have entered into a global collaboration to jointly develop and commercialise lixudebart an investigational treatment that targets claudin and could have applications across several kidney liver and other diseases

Regeneron and Sanofi Expand Collaboration to Develop Long-Acting Immunology Antibodies

Regeneron Pharmaceuticals and Sanofi have expanded their longstanding antibody collaboration to develop and commercialise a new group of longacting immunology treatments

SK pharmteco Announces $200 Million Investment to Expand Manufacturing Capacity

SK pharmteco has announced a fiveyear investment of more than million to expand and upgrade its development and manufacturing capabilities in the US focusing on small molecules and peptides

CAS and Novartis Collaborate to Advance AI-Ready Reaction Data

CAS has announced a collaboration with Novartis Biomedical Research to improve access to reaction data and support the use of artificial intelligence in scientific research